Technology
BRG drugs are a new family of therapeutic agents that, based on our preclinical study results, induce broad anticancer and antiviral effects.They deliver two active ingredients:(1) 2, -3(aminopropyl)amino ethane thiol (NCI nomenclature APAET)(2) a thiol-PEG polymer that can be varied for each BRG drugThe first active ingredient is the active form of an older FDA approved drug that has reported, in the peer-reviewed literature, anticancer and antiviral effects.
The Unmet Need:
Each year in the U.S., over 600,000 people die due to cancer. The majority of these deaths are due to the unresolved problem of drug resistance. Most fatal cancers are drug resistant.Our Solution:
Response of drug resistant tumor cellsResponse of drug sensitive tumor cellsBased on our laboratory data, BRG drugs work in human cancer types that have few to no effective treatments, and they alter tumor cell resistance to selected anticancer agents so that all to nearly all tumor cells are killed after just one exposure to the two anticancer agents together.
Advantages
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